The name “bed bug” derives from the preferred habitat of Cimex lectularius: warm houses and especially near or inside beds and bedding or other sleep areas. Bed bugs are mainly active at night, but are not exclusively nocturnal. They usually feed on their hosts without being noticed.

A number of adverse health effects may result from bed bug bites, including skin rashes, psychological effects, and allergic symptoms. They are not known to transmit any pathogens as disease vectors. Certain signs and symptoms suggest the presence of bed bugs; finding the insects confirms the diagnosis.

Bed bugs have been known as human parasites for thousands of years. At a point in the early 1940s, they were mostly eradicated in the developed world, but have increased in prevalence since 1995, likely due to pesticide resistance and governmental bans on effective pesticides. Because infestation of human habitats has been on the increase, bed bug bites and related conditions have been on the rise as well.